Hee Jae Lee Selected Research

N- (2- hydroxy- 3- (2- cyano- 3- chlorophenoxy)propyl)- 1,1- dimethyl- 2- (2- nephthyl)ethylamine

10/2017	NPS 2143, a selective calcium-sensing receptor antagonist inhibits lipopolysaccharide-induced pulmonary inflammation.
2/2017	NPS2143 Inhibits MUC5AC and Proinflammatory Mediators in Cigarette Smoke Extract (CSE)-Stimulated Human Airway Epithelial Cells.

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Hee Jae Lee Research Topics

Disease

11	Inflammation (Inflammations) 08/2019 - 01/2013
7	Neoplasms (Cancer) 02/2018 - 10/2010
4	Obesity 02/2021 - 12/2006
4	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 12/2015
3	Cognitive Dysfunction 01/2022 - 08/2011
3	Body Weight (Weight, Body) 01/2022 - 01/2016
3	Acute Lung Injury 01/2021 - 10/2017
3	Pneumonia (Pneumonitis) 08/2020 - 10/2016
3	Schizophrenia (Dementia Praecox) 09/2017 - 07/2004
2	Epilepsy (Aura) 10/2021 - 01/2006
2	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 07/2016
2	Lung Diseases (Lung Disease) 01/2021 - 01/2021
2	Lung Neoplasms (Lung Cancer) 01/2021 - 12/2002
2	Asthma (Bronchial Asthma) 01/2021 - 01/2021
2	Hyperglycemia 08/2019 - 10/2018
2	Hemorrhage 10/2018 - 08/2011
2	Insulin Resistance 10/2018 - 01/2016
2	Seizures (Absence Seizure) 01/2016 - 08/2009
2	Bipolar Disorder (Manic Depressive Psychosis) 01/2016 - 07/2004
2	Hypothermia 01/2015 - 05/2014
2	Endotoxemia 12/2014 - 05/2014
2	Sepsis (Septicemia) 12/2014 - 05/2014
2	Alcoholism (Alcohol Abuse) 10/2004 - 07/2004
1	Huntington Disease (Huntington's Disease) 10/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021
1	Parkinson Disease (Parkinson's Disease) 10/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021
1	COVID-19 01/2021
1	Idiopathic Pulmonary Fibrosis 01/2021
1	Encephalitis (Encephalitis, Rasmussen) 08/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2018
1	Anorexia 02/2018
1	Colonic Neoplasms (Colon Cancer) 02/2018
1	Urinary Retention 01/2018
1	Rectal Neoplasms (Rectal Cancer) 12/2017
1	Renal Insufficiency (Renal Failure) 10/2017
1	Breast Neoplasms (Breast Cancer) 02/2017

Drug/Important Bio-Agent (IBA)

8	LipopolysaccharidesIBA 08/2020 - 01/2005
4	SmokeIBA 08/2020 - 12/2015
4	Dronabinol (THC)FDA LinkGeneric 08/2020 - 01/2013
3	AntioxidantsIBA 02/2021 - 10/2010
3	3,4,5-trihydroxycinnamic acidIBA 08/2020 - 01/2013
3	Proteins (Proteins, Gene)FDA Link 08/2020 - 08/2005
3	nicotinamide-beta-ribosideIBA 08/2019 - 11/2015
3	Coumaric AcidsIBA 12/2014 - 01/2013
3	Biological ProductsIBA 01/2013 - 04/2009
2	AcidsIBA 01/2021 - 12/2014
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 05/2014
2	CytokinesIBA 01/2021 - 01/2013
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 08/2020 - 10/2017
2	ResveratrolIBA 08/2019 - 10/2018
2	N- (2- hydroxy- 3- (2- cyano- 3- chlorophenoxy)propyl)- 1,1- dimethyl- 2- (2- nephthyl)ethylamineIBA 10/2017 - 02/2017
2	Pharmaceutical PreparationsIBA 02/2017 - 01/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 11/2015
2	Neuroprotective AgentsIBA 01/2014 - 08/2011
2	Estrogen ReceptorsIBA 09/2004 - 01/2004
2	Estrogens (Estrogen)FDA Link 09/2004 - 01/2004
2	Estrogen Receptor alphaIBA 09/2004 - 01/2004
1	diazonaphthalenedisulfonic acid (NDS)IBA 10/2021
1	Particulate MatterIBA 01/2021
1	Vehicle Emissions (Emissions, Vehicle)IBA 01/2021
1	ChemokinesIBA 01/2021
1	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 01/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2020
1	Interleukin-6 (Interleukin 6)IBA 08/2020
1	Peroxidase (Myeloperoxidase)IBA 08/2020
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 08/2020
1	NAD (NADH)IBA 08/2020
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 08/2020
1	Sirtuin 1IBA 08/2020
1	Pancreatic Elastase (Elastase)IBA 08/2020
1	Niacinamide (Nicotinamide)FDA LinkGeneric 08/2019
1	Streptozocin (Streptozotocin)FDA Link 08/2019
1	3,3',4,5'-tetrahydroxystilbeneIBA 08/2019
1	SirtuinsIBA 08/2019
1	SugarsIBA 10/2018
1	CurcuminIBA 10/2018
1	Amyloid beta-PeptidesIBA 10/2018
1	Plant ExtractsIBA 02/2018
1	Cisplatin (Platino)FDA LinkGeneric 02/2018
1	Local Anti-Infective Agents (Antiseptics)IBA 10/2017
1	acetovanillone (apocynin)IBA 10/2017
1	Heme (Haem)IBA 10/2017
1	Chemotactic FactorsIBA 10/2017
1	Calcium-Sensing ReceptorsIBA 10/2017
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 09/2017
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 09/2017
1	Folic Acid (Vitamin M)FDA LinkGeneric 09/2017
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 09/2017
1	Vitamin K FDA Link 09/2017
1	Niacin (Nicotinic Acid)FDA LinkGeneric 09/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 02/2017
1	Tamoxifen FDA LinkGeneric 02/2017
1	Leucine (L-Leucine)FDA Link 01/2017

Therapy/Procedure

2	Oral Administration 08/2020 - 01/2006
1	Intraperitoneal Injections 01/2022
1	Drug Therapy (Chemotherapy) 02/2018
1	Colectomy 02/2018
1	Catheters 01/2018
1	Lymph Node Excision (Lymph Node Dissection) 12/2017